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‘Unusual blood clots’ should be listed as ‘very rare’ side effect of Oxford vaccine, EU regulator says | World News

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The European medicines regulator says that “unusual blood clots” should be listed as a “very rare” side-effect of the Oxford-AstraZeneca COVID vaccine.

The European Medicines Agency said it had come to its conclusion after taking into consideration all available evidence.

European Union health ministers have been told that the announcement would have an “immediate impact on vaccination plans” and “vaccine confidence”, according to an EU document seen by Reuters news agency.

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The EMA is reminding healthcare professionals and people receiving the vaccine to remain aware of the possibility of very rare cases of blood clots combined with low levels of blood platelets occurring within two weeks of vaccination.

It said so far, most of the cases reported have occurred in women under 60 years of age.

However, despite the possible link, the regulator said the overall benefit to risk ration “remains positive”.

There have been concerns over whether the Oxford-AstraZeneca vaccine is suitable for younger age groups after reports of rare blood clots on the continent, prompting several European countries to go back-and-forth on their own vaccination strategies in recent weeks.

But ahead of the EMA’s latest briefing, France, Germany and the Netherlands had all since restricted the use of the vaccine to older people over fears that younger recipients are potentially more at risk from clots.

Earlier this week, the EMA’s head of vaccine strategy said it was “increasingly difficult” to say there is “no cause and effect relationship” between the jab and “rare cases of unusual blood clots”.

The uncertainty over the Oxford-AstraZeneca jab has been held up as one of the main reasons for Europe’s sluggish vaccination programme compared to the UK, where the shot has been widely used alongside the one from Pfizer.

But the UK regulator is also investigating whether the Oxford-AstraZeneca vaccine would be suitable for young people once the rollout reaches them in the coming months.

Use of the jab for younger Britons has been reviewed following concerns at the weekend when it was revealed that of the 18.1 million people who have had the vaccine in the UK, 30 people have developed blood clots.

Seven of those people had died as of 24 March.

The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) scheduled a joint press conference with the Joint Committee on Vaccination and Immunisation for Wednesday afternoon.

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Myanmar junta releases over 23,000 prisoners but fate of detained protesters unknown | World News

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Myanmar’s junta has claimed to have pardoned and released more than 23,000 prisoners – but it is not known if the figure includes pro-democracy activists detained in the wake of February’s coup.

The release was announced to mark the new year holiday.

State broadcaster MRTV said Myanmar‘s military leader Senior General Min Aung Hlaing pardoned the 23,047 prisoners, including 137 foreigners who will be deported.

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He also reduced sentences for others.

Early prisoner releases are customary during major holidays, but this is the second time the ruling junta has done so since it ousted the elected government of Aung San Suu Kyi, triggering daily protests, arrests and deaths by security forces.

According to the Assistance Association for Political Prisoners, which monitors casualties and arrests, government forces have killed at least 726 protesters and bystanders since the takeover.

The group says 2,728 people, including Ms Suu Kyi, are in detention.

Following the release of more than 23,000 convicts to mark Union Day on 12 February, there were reports on social media that some were recruited by the authorities to carry out violence at night in residential areas to spread panic.

Heavy clashes erupted during demonstrations in Yangon on Sunday 28 March
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Heavy clashes erupted during demonstrations in Yangon on Sunday 28 March

Some areas responded by setting up their own neighbourhood watch groups.

The military said it staged the coup because a November election won by Ms Suu Kyi’s party was rigged – an assertion dismissed by the election commission.

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COVID-19: Pandemic has now killed three million across the world – as countries see surge in cases | World News

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The global death toll from coronavirus has topped three million people amid repeated setbacks in the worldwide vaccination campaign and a deepening crisis in places such as Brazil, India and France.

The number of lives lost, as compiled by Johns Hopkins University in the US, is about equal to the population of Kyiv, Ukraine; Caracas, Venezuela; or metropolitan Lisbon, Portugal.

It is bigger than Chicago (2.7 million) and equivalent to Philadelphia and Dallas combined.

However, the true number is believed to be significantly higher because of possible government concealment and the many cases overlooked in the early stages of the outbreak that began in Wuhan, China, at the end of 2019.

Worldwide, COVID-19 deaths are on the rise again, running at around 12,000 per day on average, and new cases are climbing too, eclipsing 700,000 a day.

“This is not the situation we want to be in 16 months into a pandemic, where we have proven control measures,” said Maria Van Kerkhove, one of the World Health Organisation’s leaders on COVID-19.

In Brazil, where deaths are running at about 3,000 per day, accounting for one-quarter of the lives lost worldwide in recent weeks, the crisis has been likened to a “raging inferno” by one WHO official.

A more contagious variant of the virus has been rampaging across the country.

Meanwhile, problems that India had overcome last year are coming back to haunt health officials.

Recent religious event in India could be behind the surge in cases, experts suggest
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Recent religious event in India could be behind the surge in cases, experts suggest

Only 178 ventilators were free on Wednesday afternoon in New Delhi, a city of 29 million, where 13,000 new infections were reported the previous day.

The challenges facing India reverberate beyond its borders since the country is the biggest supplier of shots to Covax, the UN-sponsored program to distribute vaccines to poorer parts of the world.

Last month, India said it would suspend vaccine exports until the virus’s spread inside the country slows.

The WHO recently described the supply situation as precarious.

Up to 60 countries might not receive any more jabs until June, by one estimate.

To date, Covax has delivered about 40 million doses to more than 100 countries, enough to cover barely 0.25% of the world’s population.

Globally, about 87% of the 700 million doses dispensed have been given out in rich countries.

While one in four people in wealthy nations have received a vaccine, in poor countries the figure is one in more than 500.

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Elon Musk’s SpaceX wins $2.9bn NASA contract to send humans to the moon | Science & Tech News

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Elon Musk’s private space company SpaceX has won a $2.9bn (£2.1bn) NASA contract to build a spacecraft to put humans on the moon.

The tech billionaire’s firm was chosen ahead of Amazon founder Jeff Bezos’ Blue Origin and defence contractor Dynetics Inc.

Steve Jurczyk, NASA’s acting administrator, said at a video conference: “We should accomplish the next landing as soon as possible. This is an incredible time to be involved in human exploration, for all humanity.”

SpaceX founder and chief engineer Elon Musk
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SpaceX founder and chief engineer Elon Musk wants to take humans to Mars

SpaceX will need to complete a test flight “to fully check out all systems with a landing on the lunar surface prior to our formal demonstration mission”, NASA official Lisa Watson-Morgan told reporters.

Mr Musk is one of the world’s richest people thanks to his 22% stake in electric car maker Tesla, now the world’s most valuable vehicle manufacturer.

His publicly stated aim is to put humans on Mars – but so far, SpaceX has mainly been used to launch satellites for his Starlink internet venture, and other satellites and space cargo.

The SpaceX programme has suffered considerable teething problems, with another failed landing for its prototype Starship spacecraft last month.

The previous three exploded at touchdown or shortly afterwards.

Those setbacks do not appear to have affected investors’ confidence in his schemes, however, as SpaceX said on Wednesday it had raised about $1.16bn (£838m) in equity financing.

SpaceX lost another Starship, here seen launching in thick fog, in a botched landing on Tuesday
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SpaceX lost another Starship, here seen launching in thick fog, in a botched landing

NASA’s plan is get back to the moon and using that as a platform to send astronauts to Mars and it is looking to team up with private companies that share its vision for space exploration.

In December, NASA announced 18 astronauts who could be involved in plans to get back to the moon by 2024.

Jeff Bezos. Pic: AP
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NASA’s decision is a setback for Jeff Bezos. Pic: AP

It’s a setback for Mr Bezos, a lifelong space enthusiast and one of the world’s richest people, who is more focused on his space venture after deciding to step down as Amazon CEO.

The NASA deal was seen as a way for Blue Origin to establish itself as a desired partner for NASA, and also putting the venture on the road to turning a profit.

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